Pantethine is a derivative of vitamin B5 pantothenic acid. It is the active, metabolically stable form of the vitamin which is used primarily for lipid metabolism and healthy adrenal function. This is a water soluble vitamin that forms a part of a group of eight vitamins known as the Vitamin B complex. Because it is a water soluble it should be added to our daily dietary intake.
Its role in the body is to increase the concentration of substances that lower blood lipids like cholesterol and triglycerides. It is a vital component of coenzyme A. This is a cofactor of many enzymatic reactions taking place in our body including those of fat and carbohydrate metabolism. Pantethine is closer in configuration to coenzyme A than naturally occurring pantothenic acid and hence more beneficial. Coenzyme A has a very important role to play in our body. It assists in the process of fat metabolism by enhancing the fatty acid oxidation taking place in organelles called mitochondria. This is the process which leads to energy production within every cell of our body.
It is considered “anti-stress” in nature. It is required for healthy adrenal cortex function and hormone production particularly in times of stress. This is the reason why the first sign of a deficiency include symptoms like fatigue, sleep disturbances, nausea and abdominal discomfort. Although a deficiency state is quite rare, supplementing your diet with certain food sources can help prevent the symptoms. Your diet should be rich in meat products like beef, turkey, duck and chicken. Organ meats like liver and kidney are particularly rich sources. Brewer’s yeast, egg yolk, whole grain bread and cereals are other important sources. Vegetables and fruits like corn, cauliflower, kale, broccoli, tomatoes and avocado contain ample amounts as well.
This vitamin has many important uses in our body. The most notable one is the lowering of blood lipids. It has a modest role to play in decreasing the levels of harmful body lipids like cholesterol, triglycerides and the “bad” low-density lipid or LDL. It also increases the level of the “good” fat in our body called high density lipid or HDL. This is how it can help lower the risk of coronary heart disease and strokes. It is also important for the production of red blood cells in our body.
Pantethine can enhance adrenal gland function and hence protects against mental and physical stress. This is why it is known as the “stress vitamin”. Pantethine also has other minor roles to play in the body. It helps to support athletic performance because of its role in energy production and also helps fight inflammation and boost the immune system.
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